We also examined the OS from T0

based on whether the patients first met criteria for bortezomib refractoriness or the IMiD criteria for inclusion in the study. The median OS from T0 was 9 months (95 CI; 7,11) for patients meeting the bortezomib criteria first, similar to 9 months (95 CI; 7,13) for patients meeting criteria for IMiDs first (P We also separately examined the outcome from the date they became refractory to bortezomib. The median OS from the time they were considered refractory to bortezomib (as defined for the purposes of the study) was 11 months (95 CI; 10,14).

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